NOW IN FULL COLOR!
Discover the science of cancer--with this newly revised, essential introduction to cancer biology and genetics
Here in one well-organized, reader-friendly volume, you'll find everything you must know about the biology underlying cancer and its treatment, supported by the latest peer-reviewed research. Written by preeminent oncology researchers and clinicians, the book highlights the full range of important oncology topics and takes you through the biological basis of current and future biological therapy as well as more traditional approaches to cancer treatment.
Presented in full color, the Fifth Edition of The Basic Science of Oncology is thoroughly updated and refreshed to reflect the latest critical thinking in oncology. For graduate students, oncologists, residents, and fellows, there can be no more useful guide to the bedrock science and practice of oncology than this all-in-one reference.
FEATURES:
The most current, evidence-based oncology primer--one that encapsulates the science of cancer causation, cancer biology, and cancer therapy
Key insights into molecular and genetic aspects of cancer familiarize you with cancer biology as applied to prognosis and personalized cancer medicine
In-depth focus on the discovery, evaluation, and biology of anti-cancer drugs, immunotherapy, and molecularly-targeted agents
Up-to-date coverage of the basic science of radiation therapy
Specific chapters/sections on intratumor heterogeneity as it relates to potential new treatment strategies--including tumor microenvironment and metabolism, tumor stem cells, and genomic/proteomic heterogeneity
NEW! Chapter Essentials synthesize chapter content in a convenient list
NEW! Color diagrams and schematics summarize important data
About the Authors Ian Tannock, MD, PhD, Professor of Medical Oncology and Hematology Princess Margaret Hospital University of Toronto Toronto, Ontario, Canada
Richard Hill, PhD Senior Scientist, Division of Experimental Therapeutics Professor of Medical Biophysics University of Toronto Toronto, Ontario, Canada
Robert Bristow, MD, PhD Clinician-Scientist, Radiation Medicine Program Princess Margaret Hospital University of Toronto Toronto, Ontario, Canada
Lea Harrington, PhD Senior Scientist, Division of Cellular and Molecular Biology University of Toronto Toronto, Ontario, Canada
Keywords: CANCER EPIDEMIOLOGY, CHEMICAL AND RADIATION CARCINOGENESIS, METHODS OF MOLECULAR ANALYSIS, GENOMIC STABILITY AND DNA REPAIR, VIRUSES AND CANCER, ONCOGENES AND TUMOR SUPPRESSOR GENES, CELLULAR SIGNALING, TUMOR GROWTH AND CELL PROLIFERATION, CELL DEATH, TUMOR PROGRESSION AND METASTASIS, ANGIOGENESIS, FUNCTIONAL AND MOLECULAR IMAGING IN ONCOLGY, MOLECULAR AND CELLULAR BASIS OF RADIOTHERAPY, THE SCIENTIFIC BASIS OF RADIOTHERAPY, PHARMACOLOGY OF ANTICANCER DRUGS, CELLULAR AND MOLECULAR BASIS OF DRUG TREATMENT FOR CANCER, DRUG RESISTANCE, HORMONES AND CANCER, CANCER AND THE IMMUNE SYSTEM, BIOLOGICAL THERAPY OF CANCER