Sexually Transmitted Diseases, Fourth Edition

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Sexually Transmitted Diseases, Fourth Edition

Sexually Transmitted Diseases, Fourth Edition

Authors: King Holmes, P. Sparling, Walter Stamm, Peter Piot, Judith Wasserheit, Lawrence Corey and Myron Cohen

Published: December 2007

eISBN: 9780071593113 007159311X | ISBN: 9780071417488

Contents

Contributors

Introduction and Overview

Part 1 History, Socioeconomic Impact, and Epidemiology of Sexually Transmitted Infections

1 Historical Perspectives on Sexually Transmitted Diseases: Challenges for Prevention and Control

2 An Economic Perspective on Sexually Transmitted Infections Including HIV in Developing Countries

3 The Transmission Dynamics of Sexually Transmitted Infections

4 The Global Epidemiology on HIV and AIDS

5 The Epidemiology of STIs and Their Social and Behavioral Determinants: Industrialized and Developing Countries

Part 2 Social and Psychological Dimensions of Sexuality

6 Social Dimensions of Adolescent Sexuality

7 Sexual Networks, Concurrency, and STD/HIV

8 Sexual Partnership Effects on STIs/HIV Transmission

9 Psychological Perspectives on Sexuality and Sexually Transmissible Diseases and HIV Infection

Part 3 Profiles of Vulnerable Populations

10 Gender and Sexually Transmitted Diseases

11 Adolescents and STDs, Including HIV Infection

12 Female Sex Workers and Their Clients in the Epidemiology and Control of Sexually Transmitted Diseases

13 Homosexual and Bisexual Behavior in Men in Relation to STDs and HIV Infection

14 Lesbian Sexual Behavior in Relation to STDs and HIV Infection

15 HIV and Other Sexually Transmitted Infections in Injection Drug Users and Crack Cocaine Smokers

16 STDs, HIV/AIDS, and Migrant Populations

Part 4 Host Immunity and Molecular Pathogenesis and STD

17 Genitourinary Immune Defense

18 Normal Genital Flora

19 Pathogenesis of Sexually Transmitted Viral and Bacterial Infections

Part 5 Sexually Transmitted Viral Pathogens

20 The Biology of HIV, SIV, and Other Lentiviruses

21 Immunology and Pathogenesis of Human Immunodeficiency Virus Infection

22 Human T-cell Lymphotropic Viruses

23 Biology of Herpesviruses

24 Genital Herpes

25 Cytomegalovirus

26 Epstein-Barr Virus Infection

27 The Biology of Genital Human Papillomaviruses

28 Genital Human Papillomavirus Infection

29 Viral Hepatitis

30 Molluscum Contagiosum

Part 6 Sexually Transmitted Bacterial Pathogens

31 Biology of Chlamydia trachomatis

32 Chlamydia trachomatis Infections of the Adult

33 Lymphogranuloma Venereum

34 Biology of Neisseria gonorrhoeae

35 Gonococcal Infections in the Adult

36 Biology of Treponemes

37 Clinical Manifestations of Syphilis

38 Endemic Treponematoses

39 Chancroid and Haemophilus ducreyi

40 Donovanosis

41 Genital Mycoplasmas

42 Bacterial Vaginosis

Part 7 Sexually Transmitted Protozoa, Fungi, and Ectoparasites

43 Trichomonas vaginalis and Trichomoniasis

44 Intestinal Protozoa: Giardia lamblia, Entamoeba histolytica, Cryptosporidium, and New and Emerging Protozoal Infections

45 Vulvovaginal Candidiasis

46 Pubic Lice and Scabies

Part 8 Overview of STD Care Management

47 STI Care Management

48 Individual-level Risk Assessment for Sexually Transmitted Infections, Including HIV

49 Anatomy and Physical Examination of the Female Genital Tract

50 Clinical Anatomy and Physical Examination of the Male Genital Tract

51 Principles of Treatment of Sexually Transmitted Diseases

52 Principles of Laboratory Diagnosis of STIs

53 Individual, Couple, and Small-Group Interventions to Reduce HIV and STI Acquisition

54 Partner Notification for Sexually Transmitted Infections Including HIV Infection: An Evidence-Based Assessment

Part 9 Management of STD Syndromes in Women

55 Lower Genital Tract Infection Syndromes in Women

56 Pelvic Inflammatory Disease

57 Cervical Neoplasia and Other STD-Related Genital Tract Neoplasias

58 Screening for Cervical Cancer

Part 10 Management of STD Syndromes in Men

59 Urethritis in Males

60 Epididymitis

61 Prostatitis Syndromes: Causes, Differential Diagnosis, and Clinical Management

Part 11 Management of Dermatologic and Extragenital Manifestations of STD and HIV Infection

62 Generalized Cutaneous Manifestations of STD and HIV Infection: Typical Presentations, Differential Diagnosis, and Management

63 Genital Ulcer Adenopathy Syndrome

64 Genital Dermatoses

65 Ocular Infections Associated with Sexually Transmitted Diseases and HIV/AIDS

66 Treatment of Chronic Viral Hepatitis

67 Arthritis Associated with Sexually Transmitted Diseases

68 Sexually Transmitted Intestinal Syndromes

Part 12 Clinical Management of HIV Infection

69 Counseling and Testing for HIV Infection

70 Clinical Laboratory Diagnosis of HIV-1 and Use of Viral RNA to Monitor Infection

71 Psychosocial Aspects of HIV Infection

72 HIV Transmission Prevention in the Context of Care

73 Antiviral Therapy of Human Immunodeficiency Virus Infection

74 Preventing Opportunistic Infections Among HIV-Infected Persons

75 Clinical Management of HIV Infection: Management of Opportunistic Infections

76 AIDS-related Malignancies

77 Management of Neurological Disease in HIV-1 Infection

Part 13 STI/HIV in Reproductive Health and Pediatrics

78 Contraception, Contraceptive Technology, and STDs

79 Sexually Transmitted Diseases and Infertility

80 Bacterial Sexually Transmitted Infections in Pregnancy

81 Pregnancy and Viral Sexually Transmitted Infections

82 Congenital Syphilis

83 Gonococcal and Chlamydial Infections in Infants and Children

84 Herpesvirus Infections in Neonates and Children: Cytomegalovirus and Herpes Simplex Virus

85 Pregnancy and Perinatal Transmission of HIV Infection

86 Pediatric HIV infection: Epidemiology, Treatment and Complications in the United States and Internationally

87 Child Sexual Abuse and STD and HIV Infection

88 The Role of Primary Care Clinicians in STD, HIV, and Hepatitis Prevention and Care

Part 14 Prevention and Control of STI and HIV Infection

89 Multilevel Approaches to STD Epidemiology and Prevention

90 STD/HIV Prevention Programs in Developed Countries

91 Integration of HIV and STD Services

92 STD-Related Health-Care SEEKING and Health Service Delivery

93 Condoms and Other Barrier Methods for Prevention of STD/HIV Infection and Pregnancy

94 Topical Microbicides and Other Chemical Barriers for the Prevention of STD/HIV Infection

95 Behavioral Interventions for Prevention of STDs and HIV Infection at the Community Level

96 Marketing, Communication, and Advocacy for Large-Scale STD/HIV Prevention and Control

97 Innovations in Public Health Surveillance for HIV/AIDS and Other STDs: Guideposts for Prevention and Care

98 Monitoring and Evaluation of Prevention and Control Programs for HIV/AIDS and Other STD

99 STD Vaccines

100 HIV Vaccines

Part 15 Special Aspects of STI/HIV Prevention and Control in Developing Countries

101 Prevention and Control of STD and HIV Infection in Developing Countries

102 Approach to the Management of HIV/AIDS in Developing Countries

103 Approach to management of STIs in Developing Countries

104 The Laboratory in the Management of STDs, HIV, and Opportunistic Infections in Developing Countries

Part 16 Special Medical, Legal, and Social Issues

105 Sexual Assault and STD

106 Legal and Political Aspects of STI Prevention in the United States: Public Duties and Private Rights

107 Ethical Challenges of the Global AIDS Epidemic

108 Information and Communication Technologies for Prevention and Control of HIV Infection and Other STIs

Appendixes

A: Clinically Significant Drug Interactions with Medications for STDs and HIV

B: Sexually Transmitted Diseases Treatment Guidelines, 2006

Index