Williams Manual of Hematology, Eighth Edition

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Williams Manual of Hematology, Eighth Edition

Williams Manual of Hematology, Eighth Edition

Authors: Marshall Lichtman

Published: May 2011

eISBN: 9780071785051 0071785051 | ISBN: 9780071622424

Contents

Preface

Part I: Initial Clinical Evaluation

1 Approach to the Patient

Part II: Disorders of Red Cells

2 Classification of Anemias and Polycythemias

3 Aplastic Anemia: Acquired and Inherited

4 Pure Red Cell Aplasia

5 Anemia of Chronic Renal Disease

6 Anemia of Endocrine Disorders

7 Congenital Dyserythropoietic Anemias

8 The Megaloblastic Anemias

9 Iron-Deficiency Anemia and Iron Overload

10 Anemia Resulting from Other Nutritional Deficiencies

11 Hereditary and Acquired Sideroblastic Anemias

12 Anemia Resulting from Marrow Infiltration

13 Anemia of Chronic Inflammation

14 Hereditary Spherocytosis, Elliptocytosis, and Related Disorders

15 Hemolytic Anemia Related to Red Cell Enzyme Defects

16 The Thalassemias

17 The Sickle Cell Diseases and Related Disorders

18 Hemoglobinopathies Associated with Unstable Hemoglobin

19 Methemoglobinemia and Other Dyshemoglobinemias

20 Traumatic Hemolytic Anemia, March and Sports-Related Hemoglobinuria, Traumatic Cardiac Hemolytic Anemia

21 Microangiopathic Hemolytic Anemia

22 Hemolytic Anemia Resulting from a Chemical or Physical Agent

23 Hemolytic Anemia Resulting from Infectious Agents

24 Hemolytic Anemia Resulting from Warm-Reacting Antibodies

25 Cryopathic Hemolytic Anemia

26 Drug-Induced Hemolytic Anemia

27 Alloimmune Hemolytic Disease of the Newborn

28 Hypersplenism and Hyposplenism

29 Polyclonal Polycythemias (Primary and Secondary)

30 The Porphyrias

Part III: Disorders of Granulocytes

31 Classification and Clinical Manifestations of Neutrophil Disorders

32 Neutropenia and Neutrophilia

33 Disorders of Neutrophil Functions

34 Eosinophils and Their Diseases

35 Basophils and Mast Cells and Their Diseases

Part IV: Disorders of Monocytes and Macrophages

36 Monocytosis and Monocytopenia

37 Inflammatory and Malignant Histiocytosis

38 Lipid Storage Disease

Part V: Principles of Therapy for Neoplastic Hematologic Disorders

39 Pharmacology and Toxicity of Antineoplastic Drugs

40 Principles of Hematopoietic Stem Cell Transplantation

Part VI: The Clonal Myeloid Disorders

41 Classification and Clinical Manifestations of the Clonal Myeloid Disorders

42 Myelodysplastic Syndromes (Clonal Cytopenias and Oligoblastic Myelogenous Leukemia)

43 Polycythemia Vera

44 Primary and Familial Thrombocythemia

45 Paroxysmal Nocturnal Hemoglobinuria (PNH)

46 The Acute Myelogenous Leukemias

47 The Chronic Myelogenous Leukemias

48 Primary Myelofibrosis

Part VII: The Polyclonal Lymphoid Diseases

49 Classification of the Polyclonal Lymphoid Disorders

50 Lymphocytosis and Lymphocytopenia

51 Primary Immunodeficiency Syndrome

52 The Acquired Immunodeficiency Syndrome

53 The Mononucleosis Syndromes

Part VIII: The Clonal Lymphoid and Plasma Cell Diseases

54 Classification and Clinical Manifestations of the Malignant Lymphoid Disorders

55 The Acute Lymphocytic Leukemias

56 The Chronic Lymphocytic Leukemias

57 Hairy Cell Leukemia

58 Large Granular Lymphocytic Leukemia

59 Hodgkin Lymphoma

60 General Considerations of Lymphoma: Epidemiology, Etiology, Heterogeneity, and Primary Extranodal Disease

61 Diffuse Large B-Cell Lymphoma

62 Follicular Lymphomas

63 Mantle Cell Lymphomas

64 Marginal Zone B-Cell Lymphoma

65 Burkitt Lymphoma

66 Cutaneous T-Cell Lymphoma (Mycosis Fungoides and Sézary Syndrome)

67 Mature T-Cell and Natural Killer Cell Lymphomas

68 Essential Monoclonal Gammopathy

69 Myeloma

70 Macroglobulinemia

71 Heavy-Chain Diseases

72 Amyloidosis

Part IX: Disorders of Platelets and Hemostasis

73 Clinical Manifestations, Evaluation, and Classi. cation of Disorders of Hemostasis

74 Thrombocytopenia

75 Reactive (Secondary) Thrombocytosis

76 Hereditary Platelet Disorders

77 Acquired Platelet Disorders

78 The Vascular Purpuras

Part X: Disorders of Coagulation Proteins

79 Hemophilia A and B

80 von Willebrand Disease

81 Hereditary Disorders of Fibrinogen

82 Inherited Deficiencies of Coagulation Factors II, V, VII, X, XI, and XIII and the Combined De. ciencies of Factors V and VIII and of the Vitamin K-Dependent Factors

83 Antibody-Mediated Coagulation Factor Deficiencies

84 Hemostatic Dysfunction Related to Liver Diseases

85 The Antiphospholipid Syndrome (Lupus Anticoagulant and Related Disorders)

86 Disseminated Intravascular Coagulation

87 Fibrinolysis and Thrombolysis

Part XI: Thrombosis and Antithrombotic Therapy

88 Principles of Antithrombotic Therapy

89 Hereditary Thrombophilia

90 Venous Thromboembolism

91 Antibody-Mediated Thrombotic Disorders: Thrombotic Thrombocytopenic Purpura and Heparin-Induced Thrombocytopenia

Part XII: Transfusion and Hemapheresis

92 Red Cell Transfusion

93 Transfusion of Platelets

94 Therapeutic Hemapheresis

Table of Normal Values

Index